Cardiochirurgia (F. Nicolini)

Unità di Ricerca:

CARDIOCHIRURGIA

Responsabile/Coordinatore: Prof. FRANCESCO NICOLINI
Sede Universitaria UNIVERSITA’ DI PARMA
Dipartimento MEDICINA E CHIRURGIA
Indirizzo: Via  A. Gramsci Nr  14,  Cap 43126 Città  Parma

tel: 0521 703282
e-mail:  francesco.nicolini@unipr.it
sito web: www.unipr.it

 Linee di ricerca:
Trattamento della cardiopatia ischemica e sue complicanze
Trattamento mini-invasivo delle valvulopatie mitro-aortiche
Trattemento transcatetere delle patologie maggiori dell’aorta
Insufficienza cardiaca
Protezione del miocardio ischemico

Laboratori/strumentazione:

L’U.O.C. di Cardiochirurgia dell’Università di Parma si compone di un reparto di degenza di 20 posti letto, un comparto operatorio con 3 sale operatorie dotate di moderni sistemi di circolazione extracoporea e assistenza circolatoria a breve termine, e un ambulatorio clinico dedicato.

Collaborazioni internazionali:

Johns Hopkins University, Baltimore, Maryland, USA
Turku University, Turku, Finland

Elenco pubblicazioni del triennio 2018- 2020:

  1. Ruggieri VG, Bounader K, Verhoye JP, Onorati F, Rubino AS, Gatti G, Tauriainen T, De Feo M, Reichart D, Dalén M, Svenarud P, Faggian G, Santarpino G, Maselli D, Gherli R, Mariscalco G, Salsano A, Nicolini F, Gherli T, Saccocci M, Airaksinen JKE, Chocron S, Perrotti A, Biancari F. Prognostic Impact of Prolonged Cross-Clamp Time in Coronary Artery Bypass Grafting. Heart Lung Circ. 2018; 27: 1476:1482
  2. Rubino AS, Gatti G, Reichart D, Tauriainen T, De Feo M, Onorati F, Pappalardo A, Chocron S, Gulbins H, Dalén M, Svenarud P, Faggian G, Franzese I, Santarpino G, Fischlein T, Maselli D, Nardella S, Gherli R, Ahmed A, Santini F, Salsano A, Nicolini F, Zanobini M, Saccocci M, Ruggieri VG, Bounader K, Mignosa C, D’Errigo P, Rosato S, Airaksinen J, Perrotti A, Biancari F. Early Outcome of Bilateral versus Single Internal Mammary Artery Grafting in the Elderly. Ann Thorac Surg. 2018; 105: 1717-1723
  3. Nicolini F, Fortuna D, Contini GA, Pacini D, Gabbieri D, Zussa C, De Palma R, Vezzani A, Gherli T. The Impact of Age on Clinical Outcomes of Coronary Artery Bypass Grafting: Long-Term Results of a Real-World Registry. Biomed Res Int. 2017;2017:9829487. doi: 10.1155/2017/9829487.
  4. Mariscalco G, Rosato S, Serraino GF, Maselli D, Dalén M, Airaksinen JKE, Reichart D, Zanobini M, Onorati F, De Feo M, Gherli R, Santarpino G, Rubino AS, Gatti G, Nicolini F, Santini F, Perrotti A, Bruno VD, Ruggieri VG, Biancari F. Prior Percutaneous Coronary Intervention and Mortality in Patients Undergoing Surgical Myocardial Revascularization: Results From the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) With a Systematic Review and Meta-Analysis. Circ Cardiovasc Interv. 2018 Feb;11(2):e005650. doi: 10.1161/CIRCINTERVENTIONS.117.005650
  5. Onorati F, Gherli R, Mariscalco G, Girdauskas E, Quintana E, Santini F, De Feo M, Sponga S, Tozzi P, Bashir M, Perrotti A, Pappalardo A, Ruggieri V, Santarpino G, Rinaldi M, Ronaldo S, Nicolini F; E-AVR Collaborators. Outcomes comparison of different surgical strategies for the management of severe aortic valve stenosis: study protocol of a prospective multicentre European registry (E-AVR registry). BMJ Open. 2018 Feb 10;8(2):e018036. doi: 10.1136/bmjopen-2017-018036.
  6. Nicolini F. Association between serum calcium, serum phosphate and aortic stenosis with implications for prevention. Eur J Prev Cardiol. 2018 25(7):753-754
  7. Agostinelli A, Carino D, Borrello B, Nicolini F. Transapical access for thoracic endovascular aortic repair to elephant trunk completion. Interact Cardiovasc Thorac Surg. 2018; 27(2):301-303
  8. Carino D, Agostinelli A, Ricci M, Romano G, Nicolini F, Gherli T. A rare case of giant lipomatous hypertrophy of the atrial septum. Acta Biomed. 2018 Mar 27;89(1):114-116. doi: 10.23750/abm.v89i1.5224
  1. Nicolini F, Santarpino G, Gatti G, Reichart D, Onorati F, Faggian G, Dalén M, Khodabandeh S, Fischlein T, Maselli D, Nardella S, Rubino AS, De Feo M, Salsano A, Gherli R, Mariscalco G, Kinnunen EM, Ruggieri VG, Bounader K, Saccocci M, Chocron S, Airaksinen J, Perrotti A, Biancari F. Utility of glycated hemoglobin screening in patients undergoing elective coronary artery surgery: Prospective, cohort study from the E-CABG registry. Int J Surg. 2018;53:354-359
  1. Agostinelli A, Carino D, Borrello B, Romano G, Vignali L, Palumbo AA, Marcato C, Gherli T, Nicolini F. Thoracic Endovascular Aortic Repair through Cardiac Apex in the Setting of Thoracic Aortic Rupture. Ann Thorac Surg. 2018;106(4):e177-e178.
  1. Nicolini F, Vezzani A, Corradi F, Gherli R, Benassi F, Manca T, Gherli T. Gender differences in outcomes after aortic aneurysm surgery should foster further research to improve screening and prevention programmes. Eur J Prev Cardiol. 2018 Jun;25(1_suppl):32-41.
  2. Mariscalco G, Maselli D, Zanobini M, Ahmed A, Bruno VD, Benedetto U, Gherli R, Gherli T, Nicolini F. Aortic centres should represent the standard of care for acute aortic syndrome. Eur J Prev Cardiol. 2018 Jun;25(1_suppl):3-14.
  3. Carino D, Agostinelli A, Molardi A, Benassi F, Gherli T, Nicolini F. The role of genetic testing in the prevention of acute aortic dissection. Eur J Prev Cardiol. 2018 Jun;25(1_suppl):15-23.
  4. Molardi A, Di Chicco MV, Carino D, Goldoni M, Ricci M, Borrello B, Gripshi F, Gherli T, Nicolini F. The use of RemoweLL oxygenator-integrated device in the prevention of the complications related to aortic valve surgery in the elderly patient: Preliminary results. Eur J Prev Cardiol. 2018 Jun;25(1_suppl):59-65.
  5. Reichart D, Rosato S, Nammas W, Onorati F, Dalén M, Castro L, Gherli R, Gatti G, Franzese I, Faggian G, De Feo M, Khodabandeh S, Santarpino G, Rubino AS, Maselli D, Nardella S, Salsano A, Nicolini F, Zanobini M, Saccocci M, Bounader K, Kinnunen EM, Tauriainen T, Airaksinen J, Seccareccia F, Mariscalco G, Ruggieri VG, Perrotti A, Biancari F. Clinical frailty scale and outcome after coronary artery bypass grafting. Eur J Cardiothorac Surg. 2018; 54: 1102-1109
  6. Leone A, Fortuna D, Gabbieri D, Nicolini F, Contini GA, Pigini F, Zussa C, De Palma R, Di Bartolomeo R, Pacini D; RERIC (Emilia Romagna Cardiac Surgery Registry) Investigators. Triple valve surgery: results from a multicenter experience. J Cardiovasc Med (Hagerstown). 2018;19(7):382-388
  7. Biancari F, Mariscalco G, Gherli R, Reichart D, Onorati F, Faggian G, Franzese I, Santarpino G, Fischlein T, Rubino AS, Maselli D, Nardella S, Salsano A, Nicolini F, Zanobini M, Saccocci M, Ruggieri VG, Bounader K, Perrotti A, Rosato S, D’Errigo P, D’Andrea V, De Feo M, Tauriainen T, Gatti G, Dalén M. Variation in Preoperative Antithrombotic Strategy, Severe Bleeding and Use of Blood Products in Coronary Artery Bypass Grafting: Results from the Multicenter E-CABG Registry. Eur Heart J Qual Care Clin Outcomes. 2018; 4(4):246-257
  8. Agostinelli A, Carino D, Borrello B, Marcato C, Volpi A, Gherli T, Nicolini F. Blunt traumatic injury to the thoracic aorta treated with thoracic endovascular aortic repair: a single-centre 20-year experience. Interact Cardiovasc Thorac Surg.2019; 28: 17-22
  9. Santarpino G, Nicolini F, De Feo M, Dalén M, Fischlein T, Perrotti A, Reichart D, Gatti G, Onorati F, Franzese I, Faggian G, Bancone C, Chocron S, Khodabandeh S, Rubino AS, Maselli D, Nardella S, Gherli R, Salsano A, Zanobini M, Saccocci M, Bounader K, Rosato S, Tauriainen T, Mariscalco G, Airaksinen J, Ruggieri VG, Biancari F. Prognostic Impact of Asymptomatic Carotid Artery Stenosis in Patients Undergoing Coronary Artery Bypass Grafting. Eur J Vasc Endovasc Surg. 2018; 56: 741-748
  10. Biancari F, Dalén M, Ruggieri VG, Demal T, Gatti G, Onorati F, Faggian G, Rubino AS, Maselli D, Gherli R, Salsano A, Saccocci M, Santarpino G, Nicolini F, Tauriainen T, De Feo M, Airaksinen J, Rosato S, Perrotti A, Mariscalco G. Prognostic Impact of Multiple Prior Percutaneous Coronary Interventions in Patients Undergoing Coronary Artery Bypass Grafting. J Am Heart Assoc. 2018 Oct 16;7(20):e010089. doi: 10.1161/JAHA.118.010089.
  11. Carino D, Singh M, Molardi A, Agostinelli A, Goldoni M, Pacini D, Nicolini F. Non-A non-B aortic dissection: a systematic review and meta-analysis. Eur J Cardiothorac Surg. 2019; 55: 653-659
  12. Khodabandeh S, Biancari F, Kinnunen EM, Mariscalco G, Airaksinen J, Gherli R, Gatti G, Demal T, Onorati F, Faggian G, De Feo M, Santarpino G, Rubino AS, Maselli D, Salsano A, Nicolini F, Zanobini M, Ruggieri VG, Bounader K, Perrotti A, Dalén M. Perioperative Bleeding in Patients With Acute Coronary Syndrome Treated With Fondaparinux Versus Low-Molecular-Weight Heparin Before Coronary Artery Bypass Grafting. Am J Cardiol. 2019; 123: 565-570
  13. Borrello B, Carino D, Agostinelli A, Budillon AM, Nicolini F. Primary Endovascular Repair of the Ascending Aorta. Innovations (Phila). 2018 Nov/Dec;13(6):448-450. doi: 10.1097/IMI.0000000000000561.
  14. Carino D, Nicolini F. Reply to Karangelis and Tagarakis. Eur J Cardiothorac Surg. 2019;56(2):424.
  15. Nicolini F. Editorial on the article entitled “Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study”. J Thorac Dis. 2018 Nov;10(Suppl 33):S3938-S3941. Impact factor = 2.027
  16. Biancari F, Ruggieri VG, Perrotti A, Gherli R, Demal T, Franzese I, Dalén M, Santarpino G, Rubino AS, Maselli D, Salsano A, Nicolini F, Saccocci M, Gatti G, Rosato S, D’Errigo P, Kinnunen EM, De Feo M, Tauriainen T, Onorati F, Mariscalco G. Comparative Analysis of Prothrombin Complex Concentrate and Fresh Frozen Plasma in Coronary Surgery. Heart Lung Circ. 2019; 28(12): 1881-1887
  17. Nicolini F. Acetylsalicylic acid on primary prevention of cardiovascular diseases. Eur J Prev Cardiol. 2019;26(7):743-745. doi: 10.1177/2047487319825923.
  18. Holm M, Biancari F, Khodabandeh S, Gherli R, Airaksinen J, Mariscalco G, Gatti G, Reichart D, Onorati F, De Feo M, Santarpino G, Rubino AS, Maselli D, Santini F, Nicolini F, Zanobini M, Kinnunen EM, Ruggieri VG, Perrotti A, Rosato S, Dalén M. Bleeding in Patients Treated With Ticagrelor or Clopidogrel Before Coronary Artery Bypass Grafting. Ann Thorac Surg. 2019;107(6):1690-1698. doi: 10.1016/j.athoracsur.2019.01.086.
  19. Nammas W, Dalén M, Rosato S, Gherli R, Reichart D, Gatti G, Onorati F, Faggian G, De Feo M, Bancone C, Chocron S, Khodabandeh S, Santarpino G, Rubino AS, Maselli D, Nardella S, Salsano A, Gherli T, Nicolini F, Zanobini M, Saccocci M, Bounader K, D’Errigo P, Kiviniemi T, Kinnunen EM, Perrotti A, Airaksinen J, Mariscalco G, Ruggieri VG, Biancari F. Impact of preoperative thrombocytopenia on the outcome after coronary artery bypass grafting. 2019;30(4):480-486.
  20. Di Mauro M, Foschi M, Dato GMA, Centofanti P, Barili F, Corte AD, Ratta ED, Cugola D, Galletti L, Santini F, Salsano A, Rinaldi M, Mancuso S, Cappabianca G, Beghi C, De Vincentiis C, Biondi A, Livi U, Sponga S, Pacini D, Murana G, Scrofani R, Antona C, Cagnoni G, Nicolini F, Benassi F, De Bonis M, Pozzoli A, Casali G, Scrascia G, Falcetta G, Bortolotti U, Musumeci F, Gherli R, Vizzardi E, Salvador L, Picichè M, Paparella D, Margari V, Troise G, Villa E, Dossena Y, Lucarelli C, Onorati F, Faggian G, Mariscalco G, Maselli D, Parolari A, Lorusso R; Italian Group of Research for Outcome in Cardiac Surgery (GIROC). Surgical treatment of isolated tricuspid valve infective endocarditis: 25-year results from a multicenter registry. Int J Cardiol. 2019 Oct 1; 292: 62-67.
  21. Carino D, Agostinelli A, El Qarra S, Gripshi F, Nicolini F. Mitral annulus calcification: current management and future challenges. Asian Cardiovasc Thorac Ann. 2019 Sep;27(7):565-572.
  22. Carino D, Molardi A, Gherli T, Nicolini F, Agostinelli A. A Case of Type I Debranching Complicated by Anastomotic Pseudoaneurysm: Do Not Ask Too Much of the Ascending Aorta. Aorta (Stamford). 2019 Apr;7(2):63-66. doi: 10.1055/s-0039-1688439. Epub 2019 Sep 17.
  23. Biancari F, Santini F, Tauriainen T, Bancone C, Ruggieri VG, Perrotti A, Gherli R, Demal T, Dalén M, Santarpino G, Rubino AS, Nardella S, Nicolini F, Zanobini M, De Feo M, Onorati F, Mariscalco G, Gatti G. Epiaortic Ultrasound to Prevent Stroke in Coronary Artery Bypass Grafting. Ann Thorac Surg. 2020 Jan;109(1):294-301.
  24. Dalén M, Biancari F; E-CABG Study Group Collaborators. Infectious complications in patients receiving ticagrelor or clopidogrel before coronary artery bypass grafting. J Hosp Infect. 2019 Sep 26. pii: S0195-6701(19)30406-2. doi: 10.1016/j.jhin.2019.09.018. [Epub ahead of print]
  25. Lorusso R, Moscarelli M, Di Franco A, Grazioli V, Nicolini F, Gherli T, De Bonis M, Taramasso M, Villa E, Troise G, Scrofani R, Antona C, Mariscalco G, Beghi C, Miceli A, Glauber M, Ranucci M, De Vincentiis C, Gaudino M. Association Between Coronary Artery Bypass Surgical Techniques and Postoperative Stroke. J Am Heart Assoc. 2019 Dec 17;8(24):e013650. doi: 10.1161/JAHA.119.013650. Epub 2019 Dec 13.
  26. Biancari F, Gatti G, Rosato S, Mariscalco G, Pappalardo A, Onorati F, Faggian G, Salsano A, Santini F, Ruggieri VG, Perrotti A, Santarpino G, Fischlein T, Saccocci M, Musumeci F, Rubino AS, De Feo M, Bancone C, Nicolini F, Kinnunen EM, Demal T, D’Errigo P, Juvonen T, Dalén M, Maselli D. Preoperative risk stratification of deep sternal wound infection after coronary surgery. Infect Control Hosp Epidemiol. 2020 Jan 20:1-8. doi: 10.1017/ice.2019.375. [Epub ahead of print]
  27. Gaibazzi N, Sartorio D, Tuttolomondo D, Napolitano F, Siniscalchi C, Borrello B, Palumbo AA, Nicolini F. Attenuation of peri-vascular fat at computed tomography to measure inflammation in ascending aorta aneurysms. Eur J Prev Cardiol. 2020 Mar 17:2047487320911846. doi: 10.1177/2047487320911846. [Epub ahead of print] No abstract available.
  28. Onorati F, Quintana E, El-Dean Z, Perrotti A, Sponga S, Ruggieri VG, Rinaldi M, Milano AD, Santini F, Chocron S, Livi U, Salizzoni S, Loizzo T, Salsano A, Di Cesare A, Faggian G, Castella M, Nicolini F. Aortic Valve Replacement for Aortic Stenosis in Low-, Intermediate-, and High-Risk Patients: Preliminary Results From a Prospective Multicenter Registry. J Cardiothorac Vasc Anesth. 2020 Mar 1. pii: S1053-0770(20)30203-2. doi: 10.1053/j.jvca.2020.02.045. [Epub ahead of print]
  29. D’Alessandro S, Guarracino F, Nicolini F, Formica F. Commentary: Shall we wait for two days more? Can we take this risk? J Thorac Cardiovasc Surg. 2020 May 1:S0022-5223(20)31032-1. doi: 10.1016/j.jtcvs.2020.04.076. Online ahead of print.
  30. Formica F, Nicolini F. Commentary: Searching for simpler parameters in the context of non-ischemic dilated cardiomyopathy. Semin Thorac Cardiovasc Surg. 2020 Jun 29:S1043-0679(20)30226-4. doi: 10.1053/j.semtcvs.2020.06.035
  31. Rubino AS, Nicolini F, Tauriainen T, Demal T, De Feo M, Onorati F, Faggian G, Bancone C, Perrotti A, Chocron S, Dalén M, Santarpino G, Fischlein T, Maselli D, Musumeci F, Santini F, Salsano A, Zanobini M, Saccocci M, Bounader K, Gatti G, Ruggieri VG, Mignosa C, Juvonen T, Mariscalco G, Biancari F. Failure to achieve a satisfactory cardiac outcome after isolated coronary surgery in low-risk patients. Interact Cardiovasc Thorac Surg. 2020 Jul 1;31(1):9-15. doi: 10.1093/icvts/ivaa062.